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■Review

Evidence of epigenetic tags in cardiac fibrosis
Pages 401-408 
Vincenzo Grimaldi, Maria Rosaria De Pascale, Alberto Zullo, Andrea Soricelli, Teresa Infante, Francesco Paolo Mancini, Claudio Napoli 

■Original Articles

Therapeutic effect of immunoadsorption and subsequent immunoglobulin substitution in patients with dilated cardiomyopathy: Results from the observational prospective Bad Berka Registry 
Pages 409-416 
Marc-Alexander Ohlow, Michele Brunelli, Matthias Schreiber, Bernward Lauer 

EGCG, a green tea catechin, attenuates the progression of heart failure induced by the heart/muscle-specific deletion of MnSOD in mice 
Pages 417-427 
Jun-ichi Oyama, Aya Shiraki, Toshiyuki Nishikido, Toyoki Maeda, Hiroshi Komoda, Takahiko Shimizu, Naoki Makino, Koichi Node 

■Original Articles

Manual thrombus aspiration during primary percutaneous coronary intervention: Impact of total ischemic time 
Pages 428-435 
Doo Sun Sim, Myung Ho Jeong, Youngkeun Ahn, Young Jo Kim, Shung Chull Chae, Taek Jong Hong, In Whan Seong, Jei Keon Chae, Chong Jin Kim, Myeong Chan Cho, Seung-Woon Rha, Jang Ho Bae, Ki Bae Seung, Seung Jung Park, other Korea Acute Myocardial Infarction Registry (KAMIR) Investigators 

Reduction of in-stent thrombus immediately after percutaneous coronary intervention by pretreatment with prasugrel compared with clopidogrel: An optical coherence tomography study 
Pages 436-441 
Takashi Kubo, Yasushi Ino, Yoshiki Matsuo, Yasutsugu Shiono, Takeyoshi Kameyama, Takashi Yamano, Yosuke Katayama, Akira Taruya, Tsuyoshi Nishiguchi, Keisuke Satogami, Kuninobu Kashiyama, Makoto Orii, Akio Kuroi, Tomoyuki Yamaguchi, Atsushi Tanaka, Takeshi Hozumi, Takashi Akasaka 

Aortic annulus displacement assessed by contrast left ventriculography during invasive coronary angiography as a predictor of adverse events 
Pages 442-448 
Shingo Kuwata, Kihei Yoneyama, Kengo Suzuki, Masaki Izumo, Kei Mizukoshi, Kohei Koyama, Yuki Ishibashi, Takanobu Mitarai, Ryo Kamijima, Ken Kongoji, Tomoo Harada, Yoshihiro J. Akashi 

Diagnostic performance of a semiconductor gamma-camera system as studied by multicenter registry 
Pages 449-455 
Taishiro Chikamori, Kenji Goto, Satoshi Hida, Masao Miyagawa, Hayato Ishimura, Kenji Uchida, Takaya Fukuyama, Teruhito Mochizuki, Akira Yamashina 

Optimal cut-off value of reverse remodeling to predict long-term outcome after cardiac resynchronization therapy in patients with ischemic cardiomyopathy 
Pages 456-461 
Akinori Sugano, Yoshihiro Seo, Masayoshi Yamamoto, Yoshie Harimura, Tomoko Machino-Ohtsuka, Tomoko Ishizu, Kazutaka Aonuma 

Deformability of the pulsating left ventricular wall: A new aspect elucidated by high resolution ultrasonic methods
Pages 462-470 
Motonao Tanaka, Tsuguya Sakamoto, Shigeo Sugawara, Yoshiaki Katahira, Kaoru Hasegawa, Hiroyuki Nakajima, Takafumi Kurokawa, Hiroshi Kanai, Hideyuki Hasegawa 

Slow pathway modification in patients presenting with only two consecutive AV nodal echo beats 
Pages 471-475 
Felix K. Wegner, Maria Silvano, Nils Bogeholz, Patrick R. Leitz, Gerrit Frommeyer, Dirk G. Dechering, Stephan Zellerhoff, Simon Kochhauser, Philipp S. Lange, Julia Kobe, Kristina Wasmer, Gerold Monnig, Lars Eckardt, Christian Pott 

Interaction between renal function and percutaneous edge-to-edge mitral valve repair using MitraClip 
Pages 476-482 
Hidehiro Kaneko, Michael Neuss, Thomas Schau, Jens Weissenborn, Christian Butter 

Degenerative changes and immune response after transcatheter aortic valve implantation. Comparison with surgical aortic valve replacement 
Pages 483-488 
Jakub Sulzenko, Petr Tousek, Viktor Kocka, Frantisek Bednar, Hana Linkova, Robert Petr, Marek Labos, Petr Widimsky 

Impact of hyperventilation and apnea on myocardial oxygenation in patients with obstructive sleep apnea – An oxygenation-sensitive CMR study 
Pages 489-494 
Francois Roubille, Kady Fischer, Dominik P. Guensch, Jean-Claude Tardif, Matthias G. Friedrich 

Clinical features of the systolic anterior motion of the mitral valve among patients without hypertrophic cardiomyopathy
Pages 495-500 
Shoko Uematsu, Atsushi Takaghi, Yasutaka Imamura, Kyomi Ashihara, Nobuhisa Hagiwara 

■Review

Emerging roles of sodium–glucose cotransporter 2 inhibitors in cardiology
Pages 501-507 
Atsushi Tanaka, Koichi Node 

■Editorial

Incretin-related drugs and cardiovascular events: A comparison of GLP-1 analogue and DPP-4 inhibitor
Pages 508-510 
Yukihito Higashi 

■Original Articles

Safety and efficacy of liraglutide treatment in Japanese type 2 diabetes patients after acute myocardial infarction: A non-randomized interventional pilot trial 
Pages 511-517 
Masataka Kajiwara, Atsushi Tanaka, Tomohiro Kawasaki, Koichi Nakao, Tomohiro Sakamoto, Shigeru Toyoda, Teruo Inoue, Nobuhiko Koga, Koichi Node 

Effects of alogliptin on fractional flow reserve evaluated by coronary computed tomography angiography in patients with type 2 diabetes: Rationale and design of the TRACT study 
Pages 518-522 
Tsuyoshi Nozue, Kazuki Fukui, Takeshi Takamura, Takashi Sozu, Kiyoshi Hibi, Satoru Kishi, Ichiro Michishita 

■Original Articles

HDL subpopulations containing apoA-I without apoA-II (LpA-I) in patients with angiographically proven coronary artery disease
Pages 523-528 
Agnieszka Kuchta, Adrian Strzelecki, Agnieszka Ćwiklińska, Marcin Gruchała, Zbigniew Zdrojewski, Barbara Kortas-Stempak, Ewa Wieczorek, Anna Gliwińska, Kamil Dąbkowski, Maciej Jankowski 

Remnant lipoproteinemia predicts cardiovascular events in patients with type 2 diabetes and chronic kidney disease
Pages 529-535 
Si Van Nguyen, Takamitsu Nakamura, Manabu Uematsu, Daisuke Fujioka, Kazuhiro Watanabe, Yosuke Watanabe, Jun-ei Obata, Kazuto Nakamura, Kiyotaka Kugiyama 

Angiotensin II receptor blockers versus angiotensin-converting enzyme inhibitors in patients with stable coronary artery disease: Prevalence, correlates, and prognostic impact (from the CORONOR study) 
Pages 542-547 
Gilles Lemesle, Nicolas Lamblin, Thibaud Meurice, Olivier Tricot, Christophe Bauters 

Mast cells are increased in the media of coronary lesions in patients with myocardial infarction and may favor atherosclerotic plaque instability 
Pages 548-554 
Koba Kupreishvili, Wessel W. Fuijkschot, Alexander B.A. Vonk, Yvo M. Smulders, Wim Stooker, Victor W.M. Van Hinsbergh, Hans W.M. Niessen, Paul A.J. Krijnen 

Influence of undernutrition at admission on clinical outcomes in patients with acute myocardial infarction 
Pages 555-560 
Sung Hee Yoo, Hyun Yi Kook, Young Joon Hong, Ju Han Kim, Youngkeun Ahn, Myung Ho Jeong 

Safety of transradial diagnostic cardiac catheterization in patients under oral anticoagulant therapy 
Pages 561-564 
Gonzalo Gallego-Sanchez, Arsenio Gallardo-Lopez, Juan Gabriel Cordoba-Soriano, Antonio Gutierrez-Diez, Driss Melehi, Maria Isabel Barrionuevo-Sanchez, Jesus Jimenez-Mazuecos 

Comparison of Edwards SAPIEN 3 versus SAPIEN XT in transfemoral transcatheter aortic valve implantation: Difference of valve selection in the real world 
Pages 565-569 
Takahide Arai, Thierry Lefevre, Thomas Hovasse, Marie-Claude Morice, Philippe Garot, Hakim Benamer, Thierry Unterseeh, Kentaro Hayashida, Yusuke Watanabe, Erik Bouvier, Bertrand Cormier, Bernard Chevalier 

Hypothesis-free secretome analysis of thoracic aortic aneurysm reinforces the central role of TGF-β cascade in patients with bicuspid aortic valve 
Pages 570-576 
Silvia Rocchiccioli, Antonella Cecchettini, Paola Panesi, Pier Andrea Farneti, Massimiliano Mariani, Nadia Ucciferri, Lorenzo Citti, Maria Grazia Andreassi, Ilenia Foffa 

Impact of moderate to severe renal impairment on long-term clinical outcomes in patients with atrial fibrillation 
Pages 577-583 
Sung Woo Cho, Jin Kyung Hwang, Kwang Jin Chun, Seung-Jung Park, Kyoung-Min Park, June Soo Kim, Young Keun On 

Good responders to catheter ablation for long-standing persistent atrial fibrillation: Clinical and genetic characteristics
Pages 584-590 
Jin-Kyu Park, Ji-Young Lee, Pil-Sung Yang, Tae-Hoon Kim, Eunsoon Shin, Junbeom Park, Jae-Sun Uhm, Boyoung Joung, Moon-Hyoung Lee, Hui-Nam Pak 

Safety of low-dose dabigatran in patients with atrial fibrillation and mild renal insufficiency 
Pages 591-595 
Hidehira Fukaya, Shinichi Niwano, Jun Oikawa, Ryo Nishinarita, Ai Horiguchi, Hironori Nakamura, Tamami Fujiishi, Tazuru Igarashi, Naruya Ishizue, Tomoharu Yoshizawa, Akira Satoh, Jun Kishihara, Masami Murakami, Junya Ako 

■Letters to the Editor

Reverse epidemiology of systolic blood pressure levels on admission with the mortality risk in heart failure: Is it a matter of obesity paradox?
Page 596 
Yen-Po Lin, Chih-Lu Han, Gen-Min Lin 

Author's reply
Page 597 
Ji Hyun Lee, Byung-Su Yoo 

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